Human ELISA Kits

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Human Creatine Kinase MB,CK-MB ELISA Kit

Catalog #: NR-R10105

Assay time	around 60 minutes
Specificity	95%
Assay Range	0 - 400 ng/ml
Size	96T
Storage	2 - 8 ℃
Expiration	18 Months from the Manufacturing Date
Background	Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho-creatine kinase, is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and utilizes ATP to create phosphocreatine (PCr) and ADP. In tissues and cells that consume ATP rapidly, especially skeletal muscle, but also brain, photoreceptor cells of the retina, hair cells of the inner ear, spermatozoa and smooth muscle, PCr serves as an energy reservoir for the rapid buffering and regeneration of ATP in situ, as well as for intracellular energy transport by the PCr shuttle or circuit. Clinically, creatine kinase is assayed in blood tests as a marker of damage of CK-rich tissue such as in myocardial infarction (heart attack), rhabdomyolysis, muscular dystrophy, autoimmune myositides and in acute renal failure. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). The CPK-MB test is a cardiac marker used to assist diagnoses of an acute myocardial infarction.
Assay principle	Sandwich ELISA
Sample type	Serum, Plasma