The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR (clustered regularly interspaced short palindromic repeats) bacterial immune systems, is becoming an essential tool for engineering the genome in diverse organisms. As an RNA-guided DNA endonuclease, Cas9 is designated to target new sites by altering its guide RNA sequen...
The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR (clustered regularly interspaced short palindromic repeats) bacterial immune systems, is becoming an essential tool for engineering the genome in diverse organisms. As an RNA-guided DNA endonuclease, Cas9 is designated to target new sites by altering its guide RNA sequence, and its development as a tool has made sequence-specific gene editing much easier. The nuclease-deactivated form of dCas9 further provides a versatile RNA-guided DNA-targeting platform for regulating and imaging the genome in nucleus, as well as for rewriting the epigenetic dynamics, all in a sequence-specific manner. With all of these progress, scientists have begun to explore the possible applications of Cas9 in biomedical research and therapeutics. Novatein Biosciences is working hard to help you in fully utilize the Cas9 related proteins, antibodies, and assay kit to advance your projects. We focus on the applications of Cas9 proteins for genome editing, regulation, and subcellular localization of target genes.
Cas9 ELISA kit Cas9 Monoclonal Antibody Cas9 monoclonal antibody, biotinylated
Cas9 NLS, S. pyogenes contains Simian virus 40(SV40) T agtigen nuclear logcalization sequence( NLS) on the N- and C- termini of the protein.
NLS‐Cas9‐EGFP-NLS is a fusion protein containing a nuclear localization sequence (NLS) on its N terminal and EGFP-NLS on the C terminal.
Recombinant dCas9 (D10A & H840A) protein is suitable for use in imaging of genomic oci in living cells and fixed cells as well as for gene expression regulation.