Excision Repair Cross-Complementing 1 Human Recombinant, GST Tag ( ERCC1 Human, GST )

Data sheet

Formulation

ERCC1is supplied in 100ug/ml in 50mM Tris-HCl (pH7.5) with 10mM L-glutathione (reduced).

Description

ERCC1 Human Recombinant produced in E.Coli encoding human full length ERCC1 is fused to a GST tag and has a total molecular mass of 61kDa (including GST). The ERCC1 is purified by proprietary chromatographic techniques.

Protein Background

ERCC1 polypeptide is essential for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which takes part in repair and mitotic intra-chromosomal recombination. NER mechanism includes dual incisions on both s

Expression host

Escherichia Coli.

Synonyms

Excision Repair Cross-complementing rodent repair deficiency complementation group 1 (includes overlapping antisense sequence), RAD10, COFS4, UV20, DNA excision repair protein ERCC-1.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.