Bax Mouse Recombinant ( Bax Mouse )

Data sheet

Formulation

The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.

Purity

Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.

Description

Bax Mouse Recombinant amino acid 38-171 produced in E.Coli is a single, non-glycosylated polypeptide chain. The Mouse Bax is purified by proprietary chromatographic techniques.

Protein Background

Bcl-2associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenov

Expression host

Escherichia Coli.

Synonyms

Apoptosis regulator BAX membrane isoform alpha, Bax, Bcl2-associated X protein.

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Mouse Bax although stable at 12°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.

References

1.Title:Bax Regulates Production of Superoxide in Both Apoptotic and Nonapoptotic Neurons: Role of Caspases.Publication:The Journal of Neuroscience, 1 December 2010, 30(48): 16114-16127; doi: 10.1523/?JNEUROSCI.2862-10.2010 The Journal of Neuroscience, 1