DDB1 and CUL4 Associated Factor 7 Human Recombinant ( DCAF7 Human )

Data sheet

Formulation

DCAF7 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.4M urea and 1mM DTT.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Description

DCAF7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids (19-295 a.a) and having a molecular mass of 33.6kDa.DCAF7 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chr

Protein Background

DDB1-and CUL4-associated factor (DCAF7) is involved in craniofacial development. The DCAF7 protein acts upstream of the EDN1 pathway and is essential for formation of the upper jaw equivalent, the palatoquadrate. The activity necessary for the EDN1 pathwa

Expression host

Escherichia Coli.

Synonyms

DDB1- and CUL4-associated factor 7, WD repeat-containing protein 68, WD repeat-containing protein An11 homolog, DCAF7, HAN11, WDR68, AN11, SWAN-1.

Reagent Appearance

Sterile filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MVYAMNWSVR PDKRFRLALG SFVEEYNNKV QLVGLDEESS EFICRNTFDH PYPTTKLMWI PDTKGVYPDL LATSGDYLRV WRVGETETRL ECLLNNNKNS DFCAPLTSFD WNEVDPYLLG TSSIDTTCTI WGLETGQVLG RVNLVSGHVK TQLIAHDKEV YDIAFSRAGG GRDMFASVGA DGSVRMFDLR HLEHSTIIYE DPQHHPLLRL CW