Hexamethylene Bis-Acetamide Inducible 1 Human Recombinant ( HEXIM1 Human )

Catalog # PT_40945

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$201.00
DescriptionHEXIM1 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 396 amino acids (1-359a.a.) and having a molecular mass of 44.8 kDa. HEXIM1 is fused to a 37 amino acid His-Tag at N-Terminus and
Product Size: 2ug
Quantity

Data sheet

Formulation
HEXIM1 solution (0.5mg/ml) containing 20mM Tris-HCl pH-8, 0.1M NaCl and 10% glycerol.
Purity
Greater than 90% as determined by SDS-PAGE.
Description
HEXIM1 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 396 amino acids (1-359a.a.) and having a molecular mass of 44.8 kDa. HEXIM1 is fused to a 37 amino acid His-Tag at N-Terminus and purified by proprietar
Protein Background
HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. HEXIM1 is a transcriptional regulator which acts as a universal RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a la
Expression host
Escherichia Coli.
Synonyms
CLP1, EDG1, HIS1, MAQ1, Protein HEXIM1, Hexamethylene bis-acetamide-inducible protein 1, Estrogen down-regulated gene 1 protein, Cardiac lineage protein 1, Menage a quatre protein 1, FLJ13562.
Reagent Appearance
Sterile filtered colorless solution.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino acid sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAE PFLSEYQHQP QTSNCTGAAA VQEELNPERP PGAEERVPEE DSRWQSRAFP QLGGRPGPEG EGSLESQPPP LQTQACPESS CLREGEKGQN GDDSSAGGDF PPPAEVEPTP EAELLAQPCH DSEASKLGAP AAGGEEEWGQ QQRQLGKKKH RRRPSKKKRH WKPYYKLTWE EKKKFDEKQS LRASRIRAEM FA
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