RLN3 Human

Data sheet

Formulation

Lyophilized from a 0.2um filtered solution in Acetonitrile and TFA.

Solubility

It is recommended to reconstitute the lyophilized RLN3 in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Description

Relaxin-3 Human Recombinant produced in E.Coli is a disulfide-linked heterodimeric, non-glycosylated, polypeptide chain containing 24 amino acids for A chain and 27 amino acids for B chain and having a molecular mass of 2.5kDa for A chain and 3kDa for B c

Protein Background

Relaxin-3 (RLN3) belongs to the relaxin family. Relaxins being endocrine and autocrine/paracrine hormones are members of the insulin gene superfamily. Relaxin, which is produced by the ovary, targets the mammalian reproductive system to ripen the cervix,

Expression host

Escherichia Coli.

Synonyms

Relaxin 3, Prorelaxin H3, RXN3, Insulin-Like Peptide INSL7, Insulin-Like Peptide 7, Insl7, ZINS4, H3, Relaxin 3 (H3), Insulin-Like 7, Relaxin-3, RLN3.

Reagent Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Stability

Lyophilized RLN3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Relaxin-3 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add

Amino acid sequence

A chain: DVLAGLSSSC CKWGCSKSEI SSLC.B chain: RAAPYGVRLCG REFIRAVIFT CGGSRW.

Biological Activity

The ED50, as measured by cAMP accumulation in human THP-1 cells, is less than 17.5ng/ml.