PTPRC Human

Data sheet

Formulation

The PTPRC solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

Purity

Greater than 95% as determined by SDS-PAGE.

Description

PTPRC Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 257 amino acids (1031-1251a.a) and having a molecular mass of 29.6kDa. PTPRC is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary

Protein Background

Protein Tyrosine Phosphatase Receptor Type C, also known as PTPRC, which is a vital regulator of T- and B-cell antigen receptor signaling, is also a part of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules which regulate a varie

Expression host

Escherichia Coli.

Synonyms

LCA, LY5, B220, CD45, T200, GP180, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, PTPRC.

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Amino acid sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSVMIA AQGPLKETIG DFWQMIFQRK VKVIVMLTEL KHGDQEICAQ YWGEGKQTYG DIEVDLKDTD KSSTYTLRVF ELRHSKRKDS RTVYQYQYTN WSVEQLPAEP KELISMIQVV KQKLPQKNSS EGNKHHKSTP LLIHCRDGSQ QTGIFCALLN LLESAETEEV VDIFQVVKAL RKARPGMVST FEQYQFLYDV IA