POLR1C Human

Data sheet

Formulation

POLR1C protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.

Purity

Greater than 80.0% as determined by SDS-PAGE.

Description

POLR1C Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 369 amino acids (1-346 a.a.) and having a molecular mass of 41.6kDa.POLR1C is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary c

Protein Background

Polymerase (RNA) I (DNA directed) Polypeptide C (POLR1C) is a subunit of both RNA polymerase I and RNA polymerase III complexes whose defects are related with Collins syndrome. POLR1C is a protein-coding gene and is part of the Pol core element

Expression host

Escherichia Coli.

Synonyms

DNA-directed RNA polymerases I and III subunit RPAC1, POLR1C, POLR1E, RPC40, Polymerase (RNA) I (DNA directed) Polypeptide C, RPA40, RPA39, DNA-directed RNA polymerases I and III 40 kDa polypeptide, RNA polymerases I and III subunit AC1, AC40, DNA-directe

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMAASQAV EEMRSRVVLG EFGVRNVHTT DFPGNYSGYD DAWDQDRFEK NFRVDVVHMD ENSLEFDMVG IDAAIANAFR RILLAEVPTM AVEKVLVYNN TSIVQDEILA HRLGLIPIHA DPRLFEYRNQ GDEEGTEIDT LQFRLQVRCT RNPHAAKDSS DPNELYVNHK VYTRHMTWIP LGNQADLFPE GTIRPVHDDI LIAQLRPGQE ID