NME2 Rat

Data sheet

Formulation

NME2 protein solution (1mg/ml) containing Phosphate Buffered Saline pH 7.4 and 10% glycerol.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Description

NME2 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 175 amino acids (1-152 a.a) and having a molecular mass of 19.7kDa. NME2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chroma

Protein Background

NME2 takes an important part in the synthesis of nucleoside triphosphates other than ATP. NME2 negatively controls Rho activity by interacting with AKAP13/LBC. NME2 acts as a transcriptional activator of the MYC gene. NME2 binds DNA non-specifically. NME2

Expression host

Escherichia Coli.

Synonyms

Nucleoside diphosphate kinase B, NDK B, NDP kinase B, Histidine protein kinase NDKB, P18.

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMANLERT FIAIKPDGVQ RGLVGEIIKR FEQKGFRLVA MKFLRASEEH LKQHYIDLKD RPFFPGLVKY MNSGPVVAMV WEGLNVVKTG RVMLGETNPA DSKPGTIRGD FCIQVGRNII HGSDSVESAE KEIGLWFKPE ELIDYKSCAH DWVYE.