MAP2K6 Human

Data sheet

Formulation

MAP2K6 protein solution (0.25mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.

Purity

Greater than 85.0% as determined by SDS-PAGE.

Description

MAP2K6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 283 amino acids (53-314 a.a) and having a molecular mass of 32kDa.MAP2K6 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chr

Protein Background

Mitogen-Activated Protein Kinase 6 (MAP2K6) is a part of the dual specificity protein kinase family. MAP2K6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. MAP2K6 is a vital component of the MAP k

Expression host

Escherichia Coli.

Synonyms

Mitogen-Activated Protein Kinase Kinase 6, PRKMK6, MEK6, MKK6, Stress-Activated Protein Kinase Kinase 3,MAPK/ERK Kinase 6, SAPK Kinase 3, EC 2.7.12.2, MAPKK, SAPKK, SAPKK3, MEK 6, Protein Kinase, Mitogen-Activated, Kinase 6 (MAP Kinase Kinase 6), Dual Spe

Reagent Appearance

Sterile Filtered clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MLEPIMELGR GAYGVVEKMR HVPSGQIMAV KRIRATVNSQ EQKRLLMDLD ISMRTVDCPF TVTFYGALFR EGDVWICMEL MDTSLDKFYK QVIDKGQTIP EDILGKIAVS IVKALEHLHS KLSVIHRDVK PSNVLINALG QVKMCDFGIS GYLVDEVAKE IDAGCKPYMA PERINPELNQ KGYSVKSDIW SLGITMIELA ILRFPYDSWG TP