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Polyclonal Anti-PPARA

FM-A10667

$320.00

Data sheet

Size 100ug/vial
Storage At -20C for one year. After reconstitution, at 4C for one month.
Form lyophilized
Ig type rabbit IgG
Immunogen/Antigen A synthetic peptide corresponding to a sequence at the C-terminal of
Reconstitution 0.2ml of distilled water will yield a concentration of 500μg/ml.

More info

Background
Peroxisome proliferator-activated receptor alpha (PPAR-alpha), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein that in humans is encoded by the PPARA gene. PPARA gene spans 83.7 kb and contains 8 exons. And the PPAR gene is mapped to chromosome 22q12-q13.1. Sher et al. (1993) cloned a cDNA for human peroxisome proliferator-activated receptor from a human liver cDNA library. The PPAR cDNA exhibited 85% and 91% DNA and deduced amino acid sequence identity, respectively, with mouse PPAR. PPAR-alpha is a transcription factor and a major regulator of lipid metabolism in the liver.

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