Platelet Factor-4 Human Recombinant ( CXCL4 ) ( PF 4 Human )

Catalog # PT_41735

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$201.00
DescriptionCXCL4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 70 amino acids and having a molecular mass of 7.8 kDa.SourceEscherichia Coli.Physical AppearanceSterile Filtered white lyophilized
Product Size: 5ug
Quantity

Data sheet

Formulation
The CXCL4 protein was lyophilized in PBS buffer pH-7.4.
Solubility
It is recommended to reconstitute the lyophilized CXCL4 in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Description
Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues.
Protein Background
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surf
Expression host
Human Platelets.
Synonyms
CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.
Reagent Appearance
Sterile Filtered white lyophilized powder.
Stability
Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
Amino acid sequence
The sequence of the first four N-terminal amino acids was determined and was found to be Glu-Ala-Glu-Glu.
Biological Activity
The ED50 of CXCL4 as determined by its ability to inhibit human FGF basic dependent proliferation of NR6R3T3 mouse fibroblasts was found to be 5-15 ug/ml.
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