Osteoprotegerin Human Recombinant, Hi-5 ( OPG Human, Hi-5 )

Data sheet

Formulation

Osteoprotegerin protein contains PBS pH-7.4 and 10% glycerol.

Purity

Greater than 85.0% as determined by SDS-PAGE.

Description

Recombinant Osteoprotegerin produced in baculovirus is a signle, glycosylated polypeptide chain containing 398 amino acid residues (22-401 a.a.), having a calculated molecular mass of 45.6 kDa. The Osteoprotegerin is fused to a 17 amino acid His tag at C-

Protein Background

Osteoprotegerin acts as decoy receptor for rankl and thereby neutralizes its function in osteoclastogenesis. OPG inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local rankl/opg rat

Expression host

Hi-5.

Synonyms

TNFRSF11B, OPG, OCIF, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TR1, MGC29565.

Reagent Appearance

Sterile Filtered colorless clear solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Amino acid sequence

ADPETFPPKY LHYDEETSHQ LLCDKCPPGT YLKQHCTAKW KTVCAPCPDH YYTDSWHTSD ECLYCSPVCK ELQYVKQECN RTHNRVCECK EGRYLEIEFC LKHRSCPPGF GVVQAGTPER NTVCKRCPDG FFSNETSSKA PCRKHTNCSV FGLLLTQKGN ATHDNICSGN SESTQKCGID VTLCEEAFFR FAVPTKFTPNWLSVLVDNLP GTKVNAESVE RIKRQHSSQE QTF