Glucagon Like Peptide-1 ( 7-36 ) Human Recombinant ( GLP 1 Human )

Data sheet

Formulation

The GLP-1 peptide was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized Glucagon Like Peptide-1 in sterile 20mM AcOH at 1mg/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 96.0% as determined by RP-HPLC.

Description

Glucagon Like Peptide-1 is a single, glycosylated, polypeptide chain containing 30 amino acids and having a molecular mass of 3297.7 Dalton.The GLP-1 is purified by proprietary chromatographic techniques.

Protein Background

Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a guthormone. The biologically active forms of GLP-1 are: GLP-1-(7-37)

Synonyms

GLP1, Glucagon Like Peptide-1, Incretin hormone.

Reagent Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Stability

Lyophilized Glucagon Like Peptide-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GLP-1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is re

Amino acid sequence

H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.

References

Title: Synthetic (+)?antroquinonol exhibits dual actions against insulin resistance by triggering AMP kinase and inhibiting dipeptidyl peptidase IV activitiesPublications: British journal of pharmacology 172.1 (2015): 38-49.Link: http://onlinelibrary.wile