Atosiban

Data sheet

Formulation

The Atosiban peptide was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized Atosiban in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 99.0% as determined by analysis by RP-HPLC.

Description

Atosiban also called ADH (Anti-Diuretic Hormone) has a molecular formula of C43H67N11O12S2, C[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2 having a Mw of 994.2 Dalton.

Protein Background

Atosiban is the first oxytocin antagonist to be specifically developed for the treatment of preterm labor. Atosiban has a specific mode of action, inhibiting oxytocin-induced uterine contractions by blocking oxytocin receptors in the uterus. Extensive cli

Reagent Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Stability

Lyophilized Atosiban although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Atosiban should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to