More info
Background: | Factor P is a 53,000 dalton cationic protein that circulates in blood in the form of dimers, trimers and tetramers. It binds rapidly to C3b on surfaces where complement has begun to activate. Factor P binds most avidly to C3b, Bb the alternative pathway C3/C5 convertase, but also binds to C3b and C3b,B complex with lower affinity. Its primary function is to stabilize the C3b, Bb complex allowing increased alternative pathway activation. |
Storage: | -70℃ or below. Avoid freeze/thaw |
Source: | Normal human serum |
Activity: Purity: | >70% versus normal human serum standard >95% by SDS-PAGE |
Molecular Weight: Size: | 53,000 Da (single chain) 100 µg/vial |
Concentration: | 1.0 mg/mL |
Buffer: | 10 mM sodium phosphate, 145 mM NaCl, pH 7.3 |
Preservative: | None, 0.22 µm filtered |