Cytochrome P450 2D6 Human Recombinant ( CYP2D6 )

Catalog # PT_40347

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$201.00
DescriptionCytochrome P450 2D6 Human Recombinant (also called liver/kidney microsomal antigen 1) produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.The LKM1 is purified by proprietary chromatographic
Product Size: 5ug
Quantity

Data sheet

Formulation
LKM-1 is supplied in 50mM Potassium phosphate buffer pH-7.5, 15% glycerol, 1mM DTT and 1% Triton X-100.
Purity
Greater than 40% as determined by SDS-PAGE.
Applications
Western-Blot with monoclonal anti-LKM-1 antibody and autoimmune hepatitis patient sera.
Description
Cytochrome P450 2D6 Human Recombinant (also called liver/kidney microsomal antigen 1) produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.The LKM1 is purified by proprietary chromatographic techniques.
Protein Background
Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes (mono-oxygenases) present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoan
Expression host
Sf9 insect cells.
Synonyms
Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1.
Reagent Appearance
Sterile filtered liquid formulation.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Immunological functions
1. Binds IgG-type human auto-antibodies.2. Standard ELISA test (checker-board analysis of positive/negative sera panels, including international reference serum NIBSC 66/387).
Coating concentration
0.35-0.6 ug/ml (depending on the type of ELISA plate and coating buffer).Suitable for biotinylation and iodination.
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