Human Endothelin-2 ( EDN2 Human )

Data sheet

Formulation

The protein (1mg/ml) was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized EDN2 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 95.0% as determined by RP-HPLC.

Description

EDN2 contains 21 amino acids having a molecular mass of 2546.97 Dalton.

Protein Background

Endothelin-2 is a Hypoxia-induced Autocrine Survival Factor for Breast Tumor Cells. The synthesis of EDN2 by human kidney carcinoma cells is decreased by EGF. EDN2 is a chemoattractant for macrophages and THP-1 monocytic cells. Chemotaxis towards EDN2 is

Synonyms

EDN2, EDN-2, vasoactive intestinal contractor peptide, VIC, ET-2, Endothelin-2, Preproendothelin-2, PPET2, ET2.

Reagent Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Stability

Lyophilized EDN2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EDN2 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a ca

Amino acid sequence

Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp.