More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| solute carrier family 12(potassium/chloride transporters), member 6 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human SLC12A6(1060-1080aa QKAKSMEGFQDLLNMRPDQSN), different from the related mouse and rat sequences by one amino acid. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | SLC12A6 |
Protein | Solute carrier family 12 member 6 |
Uniprot ID | Q9UHW9 |
Function | Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells. |
Tissue Specificity | Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level). |
Sub-cellular localization | Basolateral cell membrane ; Multi-pass membrane protein . |
Sequence Similarities | |
Aliases | ACCPN antibody|Furosemide sensitive KCl cotransporter 3 antibody|Gaxp antibody|KCC 3 antibody|KCC 3A antibody|KCC 3B antibody|KCC3 A antibody|KCC3 antibody|KCC3 B antibody|KCC3A antibody|KCC3B antibody|Potassium chloride cotransporter 3 antibody|Potassium chloride cotransporter KCC3a S3 antibody|SLC12 A6 antibody|SLC12A 6 antibody|Solute carrier family 12(potassium/chloride transporters), member 6 antibody|Solute carrier family 12, member 6 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human Mouse, Rat | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-SLC12A6 antibody, ASA-B1704, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: HUT102 Cell Lysate
Lane 1: HELA Cell Lysate
Lane 2: HUT102 Cell Lysate
