ASA-B1426
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NUR77 Antibody
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Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
nuclear receptor subfamily 4, group A, member 1 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen | ||||||
A synthetic peptide corresponding to a sequence at the N-terminus of human NUR77(99-112aa ASFKFEDFQVYGCY), identical to the related rat and mouse sequences. |
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Gene | NR4A1 |
Protein | Nuclear receptor subfamily 4 group A member 1 |
Uniprot ID | P22736 |
Function | Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. |
Tissue Specificity | Fetal muscle and adult liver, brain and thyroid. |
Sub-cellular localization | Cytoplasm. Nucleus. |
Sequence Similarities | Belongs to the nuclear hormone receptor family. NR4 subfamily. |
Aliases | Early response protein NAK1 antibody|GFRP 1 antibody|GFRP antibody|GFRP1 antibody|Growth factor inducible nuclear protein N10 antibody|Growth Factor Inducible Nuclear Protein NP10 antibody|Growth Factor Response Protein 1 antibody|Hbr1 antibody|HMR antibody|Hormone Receptor antibody|MGC9485 antibody|N10 antibody|N10 nuclear protein antibody|NAK 1 antibody|NAK1 antibody|Nerve growth factor IB nuclear receptor variant 1 antibody|NGFIB antibody|NP 10 antibody|NP10 antibody|NR4A1 antibody|NR4A1_HUMAN antibody|Nuclear hormone receptor NUR/77 antibody|Nuclear Hormone Receptor TR3 antibody|Nuclear Receptor Subfamily 4 Group A Member 1 antibody|NUR 77 antibody|NUR77 antibody|Orphan nuclear receptor HMR antibody|Orphan nuclear receptor NR4A1 antibody|Orphan nuclear receptor TR3 antibody|ST 59 antibody|ST-59 antibody|ST59 antibody|Steroid receptor TR3 antibody|Testicular receptor 3 antibody|TR 3 antibody|TR3 antibody|TR3 orphan receptor antibody |
Application | Concentration* | Species | Validated Using** |
Western blot | 0.1-0.5μg/ml | Human Mouse, Rat | AssaySolutio's ECL kit |