NUR77 Antibody View larger

NUR77 Antibody

ASA-B1426

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

nuclear receptor subfamily 4, group A, member 1 Polyclonal IgG Rabbit Human, Mouse, Rat WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human NUR77(99-112aa ASFKFEDFQVYGCY), identical to the related rat and mouse sequences.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

NR4A1

Protein

Nuclear receptor subfamily 4 group A member 1

Uniprot ID

P22736

Function

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

Tissue Specificity

Fetal muscle and adult liver, brain and thyroid.

Sub-cellular localization

Cytoplasm. Nucleus.

Sequence Similarities

Belongs to the nuclear hormone receptor family. NR4 subfamily.

Aliases

Early response protein NAK1 antibody|GFRP 1 antibody|GFRP antibody|GFRP1 antibody|Growth factor inducible nuclear protein N10 antibody|Growth Factor Inducible Nuclear Protein NP10 antibody|Growth Factor Response Protein 1 antibody|Hbr1 antibody|HMR antibody|Hormone Receptor antibody|MGC9485 antibody|N10 antibody|N10 nuclear protein antibody|NAK 1 antibody|NAK1 antibody|Nerve growth factor IB nuclear receptor variant 1 antibody|NGFIB antibody|NP 10 antibody|NP10 antibody|NR4A1 antibody|NR4A1_HUMAN antibody|Nuclear hormone receptor NUR/77 antibody|Nuclear Hormone Receptor TR3 antibody|Nuclear Receptor Subfamily 4 Group A Member 1 antibody|NUR 77 antibody|NUR77 antibody|Orphan nuclear receptor HMR antibody|Orphan nuclear receptor NR4A1 antibody|Orphan nuclear receptor TR3 antibody|ST 59 antibody|ST-59 antibody|ST59 antibody|Steroid receptor TR3 antibody|Testicular receptor 3 antibody|TR 3 antibody|TR3 antibody|TR3 orphan receptor antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human Mouse, RatAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-NUR77 antibody, ASA-B1426, Western blotting
Lane 1: A431 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: JURKAT Cell Lysate

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