More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| linker for activation of T cells family, member 2 | Polyclonal | IgG | Rabbit | Human | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the N-terminus of human NTAL(34-48aa KRSEKIYQQRSLRED). | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | LAT2 |
Protein | Linker for activation of T-cells family member 2 |
Uniprot ID | Q9GZY6 |
Function | Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. |
Tissue Specificity | Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B- cells, NK cells and monocytes. Absent from T-cells (at protein level). |
Sub-cellular localization | Cell membrane. |
Sequence Similarities | |
Aliases | HSPC046 antibody|LAB antibody|Lat2 antibody|Linker for activation of B cells antibody|Linker for activation of B-cells antibody|Linker for activation of T cells family member 2 antibody|Linker for activation of T cells transmembrane adaptor 2 antibody|Linker for activation of T-cells family member 2 antibody|Linker of Activated B cells antibody|Membrane associated adapter molecule antibody|Membrane-associated adapter molecule antibody|Non T Cell Activation Linker antibody|Non-T-cell activation linker antibody|NTAL_HUMAN antibody|WBSCR 5 antibody|Wbscr15 antibody|Williams Beuren syndrome chromosome region 15 antibody|Williams Beuren Syndrome chromosome region 5 antibody|Williams-Beuren syndrome chromosomal region 15 protein antibody|Williams-Beuren syndrome chromosomal region 5 protein antibody|WSCR5 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-NTAL antibody, ASA-B1420, Western blotting
Recombinant Protein Detection Source: E.coli derived -recombinant Human LAT2, 37.8KD(162aa tag+ M1-A182)
Lane 1: Recombinant Human LAT2 Protein 10ng
Lane 2: Recombinant Human LAT2 Protein 5ng
Lane 3: Recombinant Human LAT2 Protein 2.5ng
Lane 4: Recombinant Human LAT2 Protein 1.25ng
Recombinant Protein Detection Source: E.coli derived -recombinant Human LAT2, 37.8KD(162aa tag+ M1-A182)
Lane 1: Recombinant Human LAT2 Protein 10ng
Lane 2: Recombinant Human LAT2 Protein 5ng
Lane 3: Recombinant Human LAT2 Protein 2.5ng
Lane 4: Recombinant Human LAT2 Protein 1.25ng
