More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| glutamate receptor, ionotropic, N-methyl D-aspartate 2C | Polyclonal | IgG | Rabbit | Human, Rat | WB | Immunogen affinity purified. |
Immunogen | ||||||
| E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | GRIN2C |
Protein | Glutamate receptor ionotropic, NMDA 2C |
Uniprot ID | Q14957 |
Function | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. |
Tissue Specificity | Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas. |
Sub-cellular localization | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
Sequence Similarities | |
Aliases | GluN2C antibody|Glutamate [NMDA] receptor subunit epsilon-3 antibody| Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody|Glutamate receptor ionotropic, NMDA 2C antibody|Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody|Grin2c antibody|N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody|N Methyl D Aspartate Receptor Subtype 2C antibody|N methyl D aspartate receptor subunit 2C antibody|N-methyl D-aspartate receptor subtype 2C antibody|NMDAR2C antibody|NMDE3_HUMAN antibody|NR2C antibody|OTTHUMP00000041930 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Rat Human | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- NMDAR2C antibody, ASA-B1392, Western blotting
All lanes: Anti NMDAR2C (ASA-B1392) at 0.5ug/ml
WB: Rat Brain Tissue Lysate at 50ug
Predicted bind size: 134KD
Observed bind size: 134KD
All lanes: Anti NMDAR2C (ASA-B1392) at 0.5ug/ml
WB: Rat Brain Tissue Lysate at 50ug
Predicted bind size: 134KD
Observed bind size: 134KD
