More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| potassium voltage-gated channel, Shal-related subfamily, member 3 | Polyclonal | IgG | Rabbit | Human, Mouse | WB | Immunogen affinity purified. |
Immunogen | ||||||
| E.coli-derived human Kv4.3 recombinant protein (Position: M1-H177). Human Kv4.3 shares 100% and 99% amino acid (aa) sequences identity with mouse and rat Kv4.3, respectively. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | KCND3 |
Protein | Potassium voltage-gated channel subfamily D member 3 |
Uniprot ID | Q9UK17 |
Function | Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. |
Tissue Specificity | Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas. |
Sub-cellular localization | Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma . Cell projection, dendrite . |
Sequence Similarities | Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily. |
Aliases | KCND 3 antibody|KCND 3L antibody|KCND 3S antibody|Kcnd3 antibody|KCND3_HUMAN antibody|KCND3L antibody|KCND3S antibody|KSHIVB antibody|Kv 4.3 antibody|MGC14203 antibody|MGC142037 antibody|OTTHUMP00000063948 antibody|Potassium ioinic channel Kv4.3 antibody|Potassium voltage gated channel Shal related subfamily member 3 antibody|Potassium voltage gated channel subfamily D member 3 antibody|Potassium voltage-gated channel subfamily D member 3 antibody|Sha1 related potassium channel Kv4.3 antibody|Voltage gated K+ channel antibody|Voltage gated potassium channel Kv4.3 antibody|Voltage gated potassium channel subunit Kv4.3 antibody|Voltage-gated potassium channel subunit Kv4.3 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Mouse Human | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- Kv4.3 antibody, ASA-B1145, Western blotting
All lanes: Anti Kv4.3 (ASA-B1145) at 0.5ug/ml
WB: Mouse Brain Tissue Lysate at 50ug
Predicted bind size: 73KD
Observed bind size: 73KD
All lanes: Anti Kv4.3 (ASA-B1145) at 0.5ug/ml
WB: Mouse Brain Tissue Lysate at 50ug
Predicted bind size: 73KD
Observed bind size: 73KD
