ASA-B0775
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GCSF Receptor Antibody
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Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
Colony stimulating factor 3 receptor(granulocyte) | Polyclonal | IgG | Rabbit | Human | WB | Immunogen affinity purified. |
Immunogen | ||||||
A synthetic peptide corresponding to a sequence in the middle region of human GCSF Receptor(254-271aa EPWQPGLHINQKCELRHK). |
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Gene | CSF3R |
Protein | Granulocyte colony-stimulating factor receptor |
Uniprot ID | Q99062 |
Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
Tissue Specificity | One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta. |
Sub-cellular localization | Isoform 2: Secreted . |
Sequence Similarities | Belongs to the type I cytokine receptor family. Type 2 subfamily. |
Aliases | CD 114 antibody|CD114 antibody|CD114 antigen antibody|Colony stimulating factor 3 receptor(granulocyte) antibody|Colony stimulating factor 3 receptor antibody|CSF 3R antibody|CSF3R antibody|CSF3R_HUMAN antibody|Csfgr antibody|G CSF R antibody|G-CSF receptor antibody|G-CSF-R antibody|GCSFR antibody|Granulocyte colony stimulating factor receptor antibody|Granulocyte colony stimulating factor receptor precursor antibody|Granulocyte colony-stimulating factor receptor antibody|OTTHUMP00000009703 antibody|OTTHUMP00000009704 antibody|OTTHUMP00000009705 antibody |
Application | Concentration* | Species | Validated Using** |
Western blot | 0.1-0.5μg/ml | Human | AssaySolutio's ECL kit |