More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| dihydropyrimidine dehydrogenase | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen |
| A synthetic peptide corresponding to a sequence at the N-terminus of human DPYD(33-52aa AKKLDKKHWKRNPDKNCFNC), different from the related rat and mouse sequences by one amino acid. |
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | DPYD |
Protein | Dihydropyrimidine dehydrogenase [NADP(+)](DHPDHase/DPD) |
Uniprot ID | Q12882 |
Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
Tissue Specificity | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. |
Sub-cellular localization | Cytoplasm. |
Sequence Similarities | Belongs to the dihydropyrimidine dehydrogenase family. |
Aliases | DHP antibody|DHPDHase antibody|Dihydropyrimidine dehydrogenase[NADP(+)] antibody|Dihydropyrimidine dehydrogenase[NADP+] antibody|Dihydropyrimidine dehydrogenase antibody|Dihydrothymine dehydrogenase antibody|Dihydrouracil dehydrogenase antibody|DPD antibody|DPYD antibody|DPYD_HUMAN antibody|MGC132008 antibody|MGC70799 antibody|OTTHUMP00000058954 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human Mouse, Rat | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-DPYD antibody, ASA-B0607, Western blotting
WB: MM231 Cell Lysate
