CXCR5 Antibody View larger

CXCR5 Antibody

ASA-B0525

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

chemokine(C-X-C motif) receptor 5 Polyclonal IgG Rabbit Human, Mouse, Rat WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CXCR5(358-372aa SSLSESENATSLTTF), identical to the related rat and mouse sequences.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

CXCR5

Protein

C-X-C chemokine receptor type 5

Uniprot ID

P32302

Function

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Tissue Specificity

Expression in mature B-cells and Burkitt lymphoma cells.

Sub-cellular localization

Cell membrane; Multi-pass membrane protein.

Sequence Similarities

Belongs to the G-protein coupled receptor 1 family.

Aliases

BLR 1 antibody|BLR1 antibody|Burkitt lymphoma receptor 1 antibody|Burkitt lymphoma receptor 1 GTP binding protein antibody|C X C chemokine receptor type 5 antibody|C-X-C chemokine receptor type 5 antibody|CD 185 antibody|CD185 antibody|CD185 antigen antibody|Chemokine C X C motif receptor 5 antibody|Chemokine CXC motif receptor 5 antibody|Chemokine receptor 5 antibody|CXC chemokine receptor type 5 antibody|CXC R5 antibody|CXC-R5 antibody|CXCR 5 antibody|CXCR-5 antibody|Cxcr5 antibody|CXCR5_HUMAN antibody|MDR 15 antibody|MDR-15 antibody|MDR15 antibody|MGC117347 antibody|Monocyte derived receptor 15 antibody|Monocyte-derived receptor 15 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human, Rat MouseAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-CXCR5 antibody, ASA-B0525, Western blotting
Lane 1: Rat Spleen Tissue Lysate
Lane 2: HELA Cell Lysate

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