More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| Kv channel interacting protein 3, calsenilin | Polyclonal | IgG | Rabbit | Human | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the N-terminus of human CSEN(1-16aa MQPAKEVTKASDGSLL). | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | KCNIP3 |
Protein | Calsenilin |
Uniprot ID | Q9Y2W7 |
Function | Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). |
Tissue Specificity | Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease. |
Sub-cellular localization | Cytoplasm. |
Sequence Similarities | Belongs to the recoverin family. |
Aliases | 4933407H12Rik antibody|A type potassium channel modulatory protein 3 antibody|A-type potassium channel modulatory protein 3 antibody|AI413860 antibody|Calsenilin antibody|CSEN antibody||DRE Antagonist Modulator antibody|DRE-antagonist modulator antibody|DREAM antibody|EF Hand Transcription Factor antibody|KCHIP 3 antibody|KCHIP3 antibody|KCNIP 3 antibody|KCNIP3 antibody|Kv channel interacting protein 3 antibody|Kv channel-interacting protein 3 antibody|MGC18289 antibody|Potassium channel interacting protein 3 antibody|Presenilin Binding Protein antibody|R74849 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- CSEN antibody, ASA-B0502, Western blotting
All lanes: Anti CSEN (ASA-B0502) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: U87 Whole Cell Lysate at 40ug
Lane 3: SHG Whole Cell Lysate at 40ug
Predicted bind size: 29KD
Observed bind size: 29KD
All lanes: Anti CSEN (ASA-B0502) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: U87 Whole Cell Lysate at 40ug
Lane 3: SHG Whole Cell Lysate at 40ug
Predicted bind size: 29KD
Observed bind size: 29KD
