Claudin 6 Antibody View larger

Claudin 6 Antibody

ASA-B0461

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

Claudin 6 Polyclonal IgG Rabbit Human WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 6(204-220aa APAISRGPSEYPTKNYV).

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

CLDN6

Protein

Claudin-6

Uniprot ID

P56747

Function

Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). May act as a coreceptor for HCV entry into hepatic cells.

Tissue Specificity

Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.

Sub-cellular localization

Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .

Sequence Similarities

Belongs to the claudin family.

Aliases

Claudin-6 antibody|Claudin6 antibody|CLD6_HUMAN antibody|CLDN 6 antibody|CLDN6 antibody|OTTHUMP00000159248 antibody|Skullin 2 antibody|Skullin antibody|UNQ757/PRO1488 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml HumanAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-Claudin 6 antibody, ASA-B0461, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: SMMC Cell Lysate

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