More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| Fc fragment of IgA, receptor for | Polyclonal | IgG | Rabbit | Human | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence in the middle of human CD89(84-101aa EFVIDHMDANKAGRYQCQ). | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | FCAR |
Protein | Immunoglobulin alpha Fc receptor(IgA Fc receptor) |
Uniprot ID | P24071 |
Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. |
Tissue Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. |
Sub-cellular localization | Isoform A.1: Cell membrane; Single-pass type I membrane protein. |
Sequence Similarities | |
Aliases | CD89 antibody|Fc alpha receptor antibody|Fc fragment of IgA, receptor for antibody|FCAR antibody|FCAR_HUMAN antibody|IgA Fc receptor antibody|Immunoglobulin alpha Fc receptor antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-CD89 antibody, ASA-B0411, Western blotting
Lane 1: A549 Cell Lysate
Lane 2: U87 Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: JURKAT Cell Lysate
Lane 1: A549 Cell Lysate
Lane 2: U87 Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: JURKAT Cell Lysate
