More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| ADAM metallopeptidase with thrombospondin type 1 motif, 1 | Polyclonal | IgG | Rabbit | Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of mouse ADAMTS1(956-968aa KHYIDFCTLTQCS), different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | ADAMTS1 |
Protein | A disintegrin and metalloproteinase with thrombospondin motifs 1 |
Uniprot ID | P97857 |
Function | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity). |
Tissue Specificity | |
Sub-cellular localization | Secreted, extracellular space, extracellular matrix. |
Sequence Similarities | Contains 1 disintegrin domain. |
Aliases | A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody|A disintegrin like and metalloprotease with thrombospondin type 1 motif 1 antibody|A disintegrin-like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 1 antibody|ADAM metallopeptidase with thrombospondin type 1 motif 1 antibody|ADAM TS 1 antibody|ADAM TS1 antibody|ADAM-TS 1 antibody|ADAM-TS1 antibody|ADAMTS 1 antibody|ADAMTS antibody|ADAMTS-1 antibody|Adamts1 antibody|ATS1_HUMAN antibody|C3 C5 antibody|KIAA1346 antibody|KIAA1346, antibody|METH 1 antibody|METH-1 antibody|METH1 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Rat Mouse | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-ADAMTS1 antibody, ASA-B0036, Western blotting
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
Lane 3: Rat Brain Tissue Lysate
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
Lane 3: Rat Brain Tissue Lysate