More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| abl-interactor 2 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2(158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | ABI2 |
Protein | Abl interactor 2 |
Uniprot ID | Q9NYB9 |
Function | May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. |
Tissue Specificity | |
Sub-cellular localization | Cytoplasm . |
Sequence Similarities | Belongs to the ABI family. |
Aliases | Abelson interactor 2 antibody|ABI 2 antibody|ABI2B antibody|Abl binding protein 3 antibody|Abl interacting protein 1(SH3 containing protein) antibody|Abl interactor 2 antibody|Abl interactor protein 2b antibody|AblBP3 antibody|AIP 1 antibody|Arg binding protein 1 antibody|Arg protein tyrosine kinase binding protein antibody|ArgBP1 antibody|ARGBPIA antibody|ArgBPIB antibody|OTTHUMP00000163783 antibody|OTTHUMP00000163784 antibody|OTTHUMP00000206182 antibody|OTTHUMP00000206183 antibody|OTTHUMP00000206184 antibody|OTTHUMP00000206185 antibody|SSH3BP2 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Rat Mouse | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-ABI2 antibody, ASA-B0024, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Human Placenta Tissue Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: HELA Cell Lysate
Lane 5: JURKAT Cell Lysate
Lane 1: Rat Brain Tissue Lysate
Lane 2: Human Placenta Tissue Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: HELA Cell Lysate
Lane 5: JURKAT Cell Lysate