KCND1  Antibody View larger

KCND1 Antibody

ASA-B1108

$365.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

potassium voltage-gated channel, Shal-related subfamily, member 1 Polyclonal IgG Rabbit Human, Mouse WB Immunogen affinity purified.

Immunogen

E.coli-derived human KCND1 recombinant protein (Position: T442-L647). Human KCND1 shares 90% amino acid (aa) sequence identity with mouse KCND1.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

KCND1

Protein

Potassium voltage-gated channel subfamily D member 1

Uniprot ID

Q9NSA2

Function

Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.

Tissue Specificity

Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain.

Sub-cellular localization

Membrane; Multi-pass membrane protein. Cell projection, dendrite .

Sequence Similarities

Aliases

Kcnd1 antibody|KCND1_HUMAN antibody|Kv4.1 antibody|mShal antibody|OTTHUMP00000025805 antibody|OTTHUMP00000025806 antibody|Potassium voltage gated channel Shal related subfamily member 1 antibody|Potassium voltage gated channel subfamily D member 1 antibody|Potassium voltage-gated channel subfamily D member 1 antibody|Shal type potassium channel antibody|Voltage gated potassium channel Kv4.1 antibody|Voltage gated potassium channel subunit Kv4.1 antibody|Voltage-gated potassium channel subunit Kv4.1 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human, MouseAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- KCND1 antibody, ASA-B1108, Western blotting
All lanes: Anti KCND1 (ASA-B1108) at 0.5ug/ml
WB: Recombinant Human KCND1 Protein 0.5ng
Predicted bind size: 39KD
Observed bind size: 39KD
Anti- KCND1 antibody, ASA-B1108, Western blotting
All lanes: Anti KCND1 (ASA-B1108) at 0.5ug/ml
Lane 1: Mouse Brain Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: COLO320 Whole Cell Lysate at 40ug
Lane 4: A549 Whole Cell Lysate at 40ug
Predicted bind size: 71KD
Observed bind size: 71KD

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