More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| potassium voltage-gated channel, Shaw-related subfamily, member 1 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen | ||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human KCNC1(494-511aa EILEINRAGRKPLRGMSI), identical to the related mouse and rat sequences. | ||||||
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | KCNC1 |
Protein | Potassium voltage-gated channel subfamily C member 1 |
Uniprot ID | P48547 |
Function | Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons. |
Tissue Specificity | |
Sub-cellular localization | Cell membrane. |
Sequence Similarities | |
Aliases | C230009H10Rik antibody|FLJ41162 antibody|FLJ42249 antibody|FLJ43491 antibody|Kcr2 1 antibody|KShIIIB antibody|Kv3.1 antibody|Kv4 antibody|MGC129855 antibody|NGK2 antibody|Potassium voltage-gated channel subfamily C member 1 antibody|Shaw antibody|Voltage gated potassium channel antibody|Voltage gated potassium channel subunit Kv3.1 antibody|Voltage-gated potassium channel subunit Kv3.1 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Mouse, Rat Human | AssaySolutio's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-KCNC1 antibody, ASA-B1107, All Western blotting
All lanes: Anti-KCNC1(ASA-B1107) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 40ug
Lane 2: Human Placenta Tissue Lysate at 40ug
Lane 3: Rat Kidney Tissue Lysate at 40ug
Predicted bind size: 58KD
Observed bind size: 58KD
All lanes: Anti-KCNC1(ASA-B1107) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 40ug
Lane 2: Human Placenta Tissue Lysate at 40ug
Lane 3: Rat Kidney Tissue Lysate at 40ug
Predicted bind size: 58KD
Observed bind size: 58KD
