HSC70 Interacting Protein HIP Antibody View larger

HSC70 Interacting Protein HIP Antibody

ASA-B0898

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

suppression of tumorigenicity 13(colon carcinoma)(Hsp70 interacting protein) Polyclonal IgG Rabbit Human WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ST13(1-19aa MDPRKVNELRAFVKMCKQD), different from the related rat and mouse sequences by two amino acids.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ST13

Protein

Hsc70-interacting protein

Uniprot ID

P50502

Function

One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity).

Tissue Specificity

Sub-cellular localization

Cytoplasm .

Sequence Similarities

Belongs to the FAM10 family.

Aliases

AAG 2 antibody|AAG2 antibody|Aging associated protein 2 antibody|F10A1_HUMAN antibody|FAM10A1 antibody|FAM10A4 antibody|FLJ27260 antibody|Heat shock 70kD protein binding protein antibody|HIP antibody|HOP antibody|Hsc70 interacting protein antibody|Hsc70-interacting protein antibody|Hsp70 interacting protein antibody|HSPABP 1 antibody|HSPABP antibody|HSPABP1 antibody|MGC129952 antibody|OTTHUMP00000028873 antibody|P48 antibody|PRO0786 antibody|Progesterone receptor associated p48 protein antibody|Progesterone receptor-associated p48 protein antibody|Protein FAM10A1 antibody|Putative tumor suppressor ST13 antibody|Renal carcinoma antigen NY REN 33 antibody|Renal carcinoma antigen NY-REN-33 antibody|SNC 6 antibody|SNC6 antibody|ST 13 antibody|ST13 antibody|Suppression of tumorigenicity 13 antibody|Suppression of tumorigenicity 13(colon carcinoma) antibody|Suppression of tumorigenicity 13 protein antibody|Suppression of tumorigenicity protein 13 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml HumanAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-HSC70 Interacting Protein HIP antibody, ASA-B0898, Western blotting
Lane 1: A431 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: 293T Cell Lysate
Lane 4: JURKAT Cell Lysate
Lane 5: MCF-7 Cell Lysate

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