TRAF5 Antibody View larger

TRAF5 Antibody

ASA-B1905

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

TNF receptor-associated factor 5 Polyclonal IgG Rabbit Human WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TRAF5(62-75aa HRFCQHCILSLREL), different from the related mouse sequence by two amino acids.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

TRAF5

Protein

TNF receptor-associated factor 5

Uniprot ID

O00463

Function

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.

Tissue Specificity

Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.

Sub-cellular localization

Cytoplasm.

Sequence Similarities

Belongs to the TNF receptor-associated factor family. A subfamily.

Aliases

MGC:39780 antibody|RING finger protein 84 antibody|RING finger protein 84 antibody|RNF 84 antibody|RNF84 antibody|TNF receptor associated factor 5 antibody|TNF receptor-associated factor 5 antibody|TRAF 5 antibody|Traf5 antibody|TRAF5_HUMAN antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml HumanAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-TRAF5 antibody, ASA-B1905, Western blotting
WB: k562 Cell Lysate

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