TRAF1 Antibody View larger

TRAF1 Antibody

ASA-B1900

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

TNF receptor-associated factor 1 Polyclonal IgG Rabbit Human, Mouse WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human TRAF1(220-235aa HQSQLDRERILSLEQR), different from the related mouse sequence by one amino acid.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

TRAF1

Protein

TNF receptor-associated factor 1

Uniprot ID

Q13077

Function

Adapter molecule that regulates the activation of NF- kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein- ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Tissue Specificity

Sub-cellular localization

Sequence Similarities

Contains 1 MATH domain.

Aliases

4732496E14Rik antibody|EBI6 antibody|EBV induced protein 6 antibody|Epstein-Barr virus-induced protein 6 antibody|MGC:10353 antibody|Tnf receptor associated factor 1 antibody|TNF receptor-associated factor 1 antibody|TRAF 1 antibody|TRAF1 antibody|TRAF1_HUMAN antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human MouseAssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-TRAF1 antibody, ASA-B1900, Western blotting
Recombinant Protein Detection Source: E.coli derived -recombinant Human TRAF1, 30.6KD(162aa tag+ E174-E282)
Lane 1: Recombinant Human TRAF1 Protein 5ng
Lane 2: Recombinant Human TRAF1 Protein 2.5ng
Lane 3: Recombinant Human TRAF1 Protein 1.25ng

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