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Data sheet
| Formulation | The STAR solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT and 20% glycerol. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Description | STAR Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 243 amino acids (64-285) and having a molecular mass of 27.1 kDa.STAR is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background | STAR facilitates the fast increase in pregnenolone synthesis stimulated by tropic hormones. STAR increases pregnenolone synthesis more than four-fold and a major STAR transcription of 1.6 kb is observed in ovary and testis. Throughout the growth and differentiation period of the ovary follicle, the immunoreactivity is likely to move from the granulosa cells of early antral follicles to the theca cell layers in the adult. |
| Expression host | E.coli. |
| Synonyms | Steroidogenic acute regulatory protein, STARD1, StAR, START domain-containing protein 1, cholesterol trafficker, Mitochondrial steroid acute regulatory protein, StAR-related lipid transfer (START) domain containing 1. |
| Reagent Appearance | Sterile Filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MEETLYSDQE LAYLQQGEEA MQKALGILSN QEGWKKESQQ DNGDKVMSKV VPDVGKVFRL EVVVDQPMER LYEELVERME AMGEWNPNVK EIKVLQKIGK DTFITHELAA EAAGNLVGPR DFVSVRCAKR RGSTCVLAGM ATDFGNMPEQ KGVIRAEHGP TCMVLHPLAG SPSKTKLTWL LSIDLKGWLP KSIINQVLSQ TQVDFANHLR KRLESHPASE ARC |
More info
cholesterol trafficker, Mitochondrial steroid acute regulatory protein, StAR, STARD1, StAR-related lipid transfer (START) domain containing 1, START domain-containing protein 1, Steroidogenic acute regulatory protein