View larger
Data sheet
| Formulation | The RAB18 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 7.5) and 1mM DTT. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Description | RAB18 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 221 amino acids (1-206) and having a molecular mass of 24.5 kDa.RAB18 is fused to a 15 amino acid T7-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background | RAB18 belongs to a family of Ras-related small GTPase which is lipid-anchored to the cytoplasmic side of the cell membrane. RAB18 takes part in apical recycling, endocytosis and protein transport between early endosomes and the plasma membrane. |
| Expression host | E.coli. |
| Synonyms | RAB18 member RAS oncogene family, RAB18LI1, WARBM3, RAB18 small GTPase, ras-related protein Rab-18. |
| Reagent Appearance | Sterile Filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence | MASMTGGQQM GRGSHMDEDV LTTLKILIIG ESGVGKSSLL LRFTDDTFDP ELAATIGVDF KVKTISVDGN KAKLAIWDTA GQERFRTLTP SYYRGAQGVI LVYDVTRRDT FVKLDNWLNE LETYCTRNDI VNMLVGNKID KENREVDRNE GLKFARKHSM LFIEASAKTC DGVQCAFEEL VEKIIQTPGL WESENQNKGV KLSHREEGQG GGACGGYCSV L |
More info
RAB18 small GTPase, RAB18LI1, ras-related protein Rab-18, WARBM3, RAB18 member RAS oncogene family