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DCN1 Defective in Cullin Neddylation 1 Domain Containing 1 Human Recombinant ( DCUN1D1 Human )
Data sheet
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles. |
| Formulation | The DCUN1D1 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 0.1M NaCl and 10% glycerol. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Description | DCUN1D1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 279 amino acids (1-259a.a.) and having a molecular mass of 32.2kDa. DCUN1D1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background | DCUN1D1 takes part in the malignant transformation of squamous cell lineage. DCUN1D1 protein regulates Gli1, a main regulator of the hedgehog (HH) pathway which takes a vital role in development, maintenance, and regeneration of practically all adult tissues. |
| Expression host | Escherichia Coli. |
| Synonyms | DCN1, defective in cullin neddylation 1-domain containing 1 (S. cerevisiae), RP42, DCUN1L1, SCCRO, SCRO, Tes3, Defective in cullin neddylation protein 1-like protein 1, Squamous cell carcinoma-related oncogene, DCUN1 domain-containing protein 1, DCN1-like protein 1, RP42 homolog. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV |
More info
DCN1-like protein 1, DCUN1 domain-containing protein 1, DCUN1L1, defective in cullin neddylation 1-domain containing 1 (S. cerevisiae), Defective in cullin neddylation protein 1-like protein 1, RP42, RP42 homolog, SCCRO, SCRO, Squamous cell carcinoma-related oncogene, Tes3, DCN1