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C-Reactive Protein Human ( CRP Human )
DescriptionHuman CRP produced in Human plasma having a molecular mass of 114 kDa. It can be used as a marker for inflammation and also used for monitoring and prediction of future events in coronary artery disease.SourceHuman Plasma.Physical
Data sheet
| Formulation | The protein solution is in 20mM TRIS buffer pH 8.0 containing 0.28M NaCl, 0.09% NaN3 and 5mM CaCl2. |
| Purity | Greater than 96.0%. |
| Description | Human CRP produced in Human plasma having a molecular mass of 114 kDa. It can be used as a marker for inflammation and also used for monitoring and prediction of future events in coronary artery disease. |
| Protein Background | CRP is an acute phase protein that correlates with inflammatory disease and is synthesized by hepatocytes during the acute phase response by certain cytokines (IL-1 and TNF Alpha and Beta). CRP levels increase dramatically ( up to 1,000 fold) and serve as a useful marker of inflammation in such conditions as bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels. |
| Expression host | Human Plasma. |
| Synonyms | C-reactive protein, CRP, PTX1, MGC88244, MGC149895. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | Human CRP should be stored at 2-8°C. Do not freeze! |
| References | Title: Elevation of Intact and Proteolytic Fragments of Acute Phase Proteins Constitutes the Earliest Systemic Antiviral Response in HIV-1 InfectionPublication: PLoS pathogens 6.5 (2010): e1000893.Link: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1000893#ppat-1000893-g006 |