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Core Binding Factor Beta Human Recombinant ( CBFB HUman )
DescriptionCBFB Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (1-202 a.a.) and having a molecular mass of 23.6 kDa. The CBFB is fused to 20 amino acid His-Tag at N-terminus and
Data sheet
| Formulation | 0.5mg/ml solution containing 20mM MES pH-6, 0.1mM PMSF & 10% glycerol. |
| Purity | Greater than 85.0% as determined by SDS-PAGE. |
| Description | CBFB Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (1-202 a.a.) and having a molecular mass of 23.6 kDa. The CBFB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
| Protein Background | CBFB beta subunit is a heterodimeric core-binding transcription factor that is part of the PEBP2/CBF transcription factor family which controls a host of genes particulary to hematopoiesis and osteogenesis. CBFB is a non-DNA binding regulatory subunit which increases DNA binding by alpha subunit. |
| Expression host | Escherichia Coli. |
| Synonyms | PEBP2B, polyomavirus enhancer binding protein b, PEA2, CBF-beta. |
| Stability | CBFB Human although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIAFVAT GTNLSLQFFPASWQGEQRQT PSREYVDLER EAGKVYLKAP MILNGVCVIW KGWIDLQRLD GMGCLEFDEE RAQQEDALAQ QAFEEARRRT REFEDRDRSHREEMEVRVSQ LLAVTGKKTT RP. |
| Physical Appearence | Sterile filtered colorless solution. |