Core Binding Factor Beta Human Recombinant ( CBFB HUman )

Data sheet

Formulation

0.5mg/ml solution containing 20mM MES pH-6, 0.1mM PMSF & 10% glycerol.

Purity

Greater than 85.0% as determined by SDS-PAGE.

Description

CBFB Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (1-202 a.a.) and having a molecular mass of 23.6 kDa. The CBFB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary

Protein Background

CBFB beta subunit is a heterodimeric core-binding transcription factor that is part of the PEBP2/CBF transcription factor family which controls a host of genes particulary to hematopoiesis and osteogenesis. CBFB is a non-DNA binding regulatory subunit whi

Expression host

Escherichia Coli.

Synonyms

PEBP2B, polyomavirus enhancer binding protein b, PEA2, CBF-beta.

Stability

CBFB Human although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIAFVAT GTNLSLQFFPASWQGEQRQT PSREYVDLER EAGKVYLKAP MILNGVCVIW KGWIDLQRLD GMGCLEFDEE RAQQEDALAQ QAFEEARRRT REFEDRDRSHREEMEVRVSQ LLAVTGKKTT RP.

Physical Appearence

Sterile filtered colorless solution.