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Copper Metabolism Domain Containing 1 Human Recombinant ( COMMD1 Human )
DescriptionCOMMD1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-190 a.a.) and having a molecular mass of 23.3 kDa. The COMMD1 is fused to 20 amino acid His-Tag at N-terminus and
Data sheet
| Formulation | COMMD1 Human solution containing 20mM Trsi pH-8, 0.1M NaCl& 20% glycerol. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Description | COMMD1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-190 a.a.) and having a molecular mass of 23.3 kDa. The COMMD1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
| Protein Background | COMMD1 is accountable for inhibition of TNF-induced NFB p50 and n facilitats of biliary copper excretion within hepatocytes. High expression of COMMD1 is localized in liver tissue, with lower expressions in lung, heart, kidney and brain tissue. COMMD1 interacts directly with COMMD6 and ATP7B, and indirectly with IB-β and COMMD7. |
| Expression host | Escherichia Coli. |
| Synonyms | MURR1, C2orf5, COMMD1, Copper Metabolism Domain Containing 1, MGC27155. |
| Reagent Appearance | Sterile filtered colorless solution. |
| Stability | COMMD1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFNQLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN. |