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Complement Component C4c Human ( C4c Human )
DescriptionHuman C4c produced in Human plasma having a molecular mass of 210 kDa.SourceHuman Plasma.Physical AppearanceSterile Filtered clear solution.FormulationThe Human Complement C4c solution is in Sodium Phosphate buffer pH 7.0 containing 0.15M
Data sheet
| Formulation | The Human Complement C4c solution is in Sodium Phosphate buffer pH 7.0 containing 0.15M NaCl and 0.09% NaN3. |
| Purity | Greater than 99.0%. |
| Description | Human C4c produced in Human plasma having a molecular mass of 210 kDa. |
| Protein Background | Complement C4c is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c.Complement C4c interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes. |
| Expression host | Human Plasma. |
| Synonyms | Complement C4c, Complement Component C4c, C4c. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | Human C4c although stable at 4°C for 1 week, should be stored at -15°C.Please avoid freeze-thaw cycles. |