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Heat Shock 70kDa Protein 6 Human Recombinant ( HSPA6 Human )
DescriptionRecombinant Human HSPA6 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 663 amino acids (2-650 a.a.) and having a molecular mass of 73.2 kDa.HSPA6 human recombinant is fused to an 8 amino acid His Tag at
Data sheet
| Formulation | The HSPA6 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl & 10% Glycerol. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Description | Recombinant Human HSPA6 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 663 amino acids (1-643 a.a) and having a molecular mass of 73.2kDa.HSPA6 human recombinant is fused to a 20 amino acid His Tag at N-terminus and purified by conventional chromatography techniques. |
| Protein Background | HSPA6 is a distinctive member of the human Hsp70 chaperone that takes part in cellular processes such as protein trafficking, folding, and prevention of aggregation. HSPA6 is strictly stress-inducible, having little or no basal expression levels in most cells. HSPA6 and HSP72 are are involved in cell survival of proteotoxic stress. |
| Expression host | Escherichia Coli. |
| Synonyms | HSP70B, Heat shock 70 kDa protein 6, Heat shock 70 kDa protein B', HSPA6. |
| Reagent Appearance | Sterile filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MQAPRELAVG IDLGTTYSCV GVFQQGRVEI LANDQGNRTT PSYVAFTDTE RLVGDAAKSQ AALNPHNTVF DAKRLIGRKF ADTTVQSDMK HWPFRVVSEG GKPKVRVCYR GEDKTFYPEE ISSMVLSKMK ETAEAYLGQP VKHAVITVPA YFNDSQRQAT KDAGAIAGLN VLRIINEPTA AAIAYGLDRR GAGERNVLIF DLGGGTFDVS VLSIDAGVFE VKATAGDTHL GGEDFDNRLV NHFMEEFRRK HGKDLSGNKR ALRRLRTACE RAKRTLSSST QATLEIDSLF EGVDFYTSIT RARFEELCSD LFRSTLEPVE KALRDAKLDK AQIHDVVLVG GSTRIPKVQK LLQDFFNGKE LNKSINPDEA VAYGAAVQAA VLMGDKCEKV QDLLLLDVAP LSLGLETAGG VMTTLIQRNA TIPTKQTQTFTTYSDNQPGV FIQVYEGERA MTKDNNLLGR FELSGIPPAP RGVPQIEVTF DIDANGILSV TATDRSTGKA NKITITNDKG RLSKEEVERM VHEAEQYKAE DEAQRDRVAA KNSLEAHVFH VKGSLQEESL RDKIPEEDRR KMQDKCREVL AWLEHNQLAE KEEYEHQKRE LEQICRPIFS RLYGGPGVPG GSSCGTQARQ GDPSTGPIIE EVD. |