Myeloid Cell Nuclear Differentiation Antigen Human Recombinant ( MNDA Human )

Data sheet

Formulation

The MNDA solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Description

MNDA Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 427 amino acids (1-407 a.a.) and having a molecular mass of 47.9 kDa. The MNDA is fused to a 20 amino acid His Tag at N-terminus and purified by propriet

Protein Background

MNDA plays a role as a transcriptional activator/repressor in the myeloid lineage and in the granulocyte/monocyte cell-specific response to interferon. MNDA Stimulates the DNA binding of the transcriptional repressor protein YY1. MNDA is identified only i

Expression host

Escherichia Coli.

Synonyms

PYHIN3, Myeloid cell nuclear differentiation antigen, MNDA.

Reagent Appearance

Sterile Filtered colorless solution.

Stability

MNDA although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MVNEYKKILL LKGFELMDDY HFTSIKSLLA YDLGLTTKMQ EEYNRIKITD LMEKKFQGVA CLDKLIELAK DMPSLKNLVN NLRKEKSKVA KKIKTQEKAP VKKINQEEVG LAAPAPTARN KLTSEARGRI PVAQKRKTPN KEKTEAKRNK VSQEQSKPPG PSGASTSAAV DHPPLPQTSS STPSNTSFTP NQETQAQRQV DARRNVPQND PV

Protein concentration

Lateral flow immunoassay.

link

Purified monoclonal IgG by protein A chromatography.