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Synaptosomal-associated protein 23 Human Recombinant ( SNAP23 Human )
DescriptionSNAP23 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 211 amino acids and having a molecular mass of 23.3 kDa.SourceEscherichia Coli.Physical AppearanceSterile Filtered colorless
Data sheet
| Formulation | The protein solution contains 20mM Tris-HCl pH-8. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Description | SNAP23 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 211 amino acids and having a molecular mass of 23.3 kDa. |
| Protein Background | SNAP23 is a non-neuronal SNAP25 protein homologue and a target SNARE ubiquitously expressed on the plasma membrane and other intracellular membranes. SNAP23 is involved in exocytotic membrane fusion in most cells that do not express SNAP-25. SNAP23 is an essential component of the high affinity receptor for the general membrane fusion machinery and an crucial regulator of transport vesicle docking and fusion. SNAP23 is phosphorylated in platelets through cell activation during a protein kinase C-related mechanism at two or more sites. SNAP23, the ubiqitously expressed homologue of SNAP25, interacts directly with ubiquitous kinesin heavy chain (uKHC). SNAP-23 is expressed in human eosinophils and is a candidates for association with VAMP-2 during docking, which is followed by exocytosis. |
| Expression host | Escherichia Coli. |
| Synonyms | SNAP23A, SNAP23B, HsT17016, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23, SNAP23. |
| Reagent Appearance | Sterile Filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence | MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE QLNRIEEGLD QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG PVTNGQLQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ NPQIKRITDK ADTNRDRIDI ANARAKKLID S. |