Stromal Interaction Molecule 1 Human Recombinant ( STIM1 Human )

Data sheet

Formulation

The STIM1 protein solution (1mg/ml) contains 20mM Tris-HCl pH-7.5.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Description

Recombinant STIM1 produced in E.Coli is a single, non-glycosylated polypeptide chain (aa 23-213) containing a total of 343 amino acids and having a molecular mass of 38kDa. STIM1 is fused to a 152 aa Calmodulin tag at N-terminus and purified by convention

Protein Background

STIM1 is a type-1 transmembrane protein that is necessary for store-operated Ca(2+) entry, a process of extracellular Ca(2+) influx in response to the depletion of Ca(2+) stores in the endoplasmic reticulum (ER). STIM1 localizes predominantly to the ER; u

Expression host

Escherichia Coli.

Synonyms

Stromal interaction molecule 1, GOK, D11S4896E, STIM-1, STIM1.

Reagent Appearance

Sterile filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Amino acid sequence

MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SMLSHSHSEK ATGTSSGANS EESTAAEFCR IDKPLCHSED EKLSFEAVRN IHKLMDDDAN GDVDVEESDE FLREDLNYHD PT