Stress-Induced-Phosphoprotein 1 Human Recombinant ( STIP1 Human )

Data sheet

Formulation

STIP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl (pH 8.0), 10% glycerol, 1mM DTT and 0.1M NaCl.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Description

STIP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 543 amino acids (1-543 a.a) and having a molecular mass of 62.6kDa. STIP1 is purified by proprietary chromatographic techniques.

Protein Background

STIP1 is an adaptor protein that mediates the functions of HSP70 & HSP90 in protein folding. STIP1 supports the transfer of proteins from HSP70 to HSP90 by binding together HSP90 and substrate-bound HSP70. STIP1 stimulates the ATPase activity of HSP70 and

Expression host

Escherichia Coli.

Synonyms

Stress Induced Phosphoprotein 1, Transformation-Sensitive Protein IEF SSP 3521, Renal Carcinoma Antigen NY-REN-11, Stress-Induced-Phosphoprotein 1, Hsp70/Hsp90-Organizing Protein, Hsc70/Hsp90-Organizing Protein, STI1, HOP, Epididymis Secretory Sperm Bindi

Reagent Appearance

Sterile Filtered colorless solution.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Amino acid sequence

MEQVNELKEK GNKALSVGNI DDALQCYSEA IKLDPHNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNPQLKE GLQNMEARLA ERKFMNPFNM PNLYQKLESD PRTRTLLSDP TYRELIEQLR NKPSDLGTKL QDPRIMTTLS VLLGVDLGSM DEEEEIATPP PPPPPKKETK PEPMEEDLPE NKKQALKEKE LG